2rsp: Difference between revisions

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{{Seed}}
[[Image:2rsp.png|left|200px]]


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==STRUCTURE OF THE ASPARTIC PROTEASE FROM ROUS SARCOMA RETROVIRUS REFINED AT 2 ANGSTROMS RESOLUTION==
The line below this paragraph, containing "STRUCTURE_2rsp", creates the "Structure Box" on the page.
<StructureSection load='2rsp' size='340' side='right'caption='[[2rsp]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2rsp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RSP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RSP FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rsp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rsp OCA], [https://pdbe.org/2rsp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rsp RCSB], [https://www.ebi.ac.uk/pdbsum/2rsp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rsp ProSAT]</span></td></tr>
{{STRUCTURE_2rsp| PDB=2rsp |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/GAG_RSVP GAG_RSVP] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity).  The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rs/2rsp_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rsp ConSurf].
<div style="clear:both"></div>


===STRUCTURE OF THE ASPARTIC PROTEASE FROM ROUS SARCOMA RETROVIRUS REFINED AT 2 ANGSTROMS RESOLUTION===
==See Also==
 
*[[Virus protease 3D structures|Virus protease 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_2166563}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 2166563 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_2166563}}
 
==About this Structure==
2RSP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RSP OCA].
 
==Reference==
Structure of the aspartic protease from Rous sarcoma retrovirus refined at 2-A resolution., Jaskolski M, Miller M, Rao JK, Leis J, Wlodawer A, Biochemistry. 1990 Jun 26;29(25):5889-98. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2166563 2166563]
[[Category: Rous sarcoma virus]]
[[Category: Rous sarcoma virus]]
[[Category: Single protein]]
[[Category: Jaskolski M]]
[[Category: Jaskolski, M.]]
[[Category: Miller M]]
[[Category: Miller, M.]]
[[Category: Wlodawer A]]
[[Category: Wlodawer, A.]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 00:58:08 2008''

Latest revision as of 09:23, 21 February 2024

STRUCTURE OF THE ASPARTIC PROTEASE FROM ROUS SARCOMA RETROVIRUS REFINED AT 2 ANGSTROMS RESOLUTION

2rsp, resolution 2.00Å

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