302d: Difference between revisions

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{{Seed}}
[[Image:302d.png|left|200px]]


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==META-HYDROXY ANALOGUE OF HOECHST 33258 ('HYDROXYL IN' CONFORMATION) BOUND TO D(CGCGAATTCGCG)2==
The line below this paragraph, containing "STRUCTURE_302d", creates the "Structure Box" on the page.
<StructureSection load='302d' size='340' side='right'caption='[[302d]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[302d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=302D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=302D FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RO2:3-[5-[5-(4-METHYL-PIPERAZIN-1-YL)-1H-IMIDAZO[4,5-B]PYRIDIN-2-YL]-BENZIMIDAZOL-2-YL]-PHENOL'>RO2</scene></td></tr>
{{STRUCTURE_302d|  PDB=302d  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=302d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=302d OCA], [https://pdbe.org/302d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=302d RCSB], [https://www.ebi.ac.uk/pdbsum/302d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=302d ProSAT]</span></td></tr>
 
</table>
===META-HYDROXY ANALOGUE OF HOECHST 33258 ('HYDROXYL IN' CONFORMATION) BOUND TO D(CGCGAATTCGCG)2===
__TOC__
 
</StructureSection>
 
[[Category: Large Structures]]
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[[Category: Clark GR]]
The line below this paragraph, {{ABSTRACT_PUBMED_9017011}}, adds the Publication Abstract to the page
[[Category: Gray EJ]]
(as it appears on PubMed at http://www.pubmed.gov), where 9017011 is the PubMed ID number.
[[Category: Leupin W]]
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[[Category: Neidle S]]
{{ABSTRACT_PUBMED_9017011}}
[[Category: Squire CJ]]
 
==About this Structure==
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=302D OCA].  
 
==Reference==
Designer DNA-binding drugs: the crystal structure of a meta-hydroxy analogue of Hoechst 33258 bound to d(CGCGAATTCGCG)2., Clark GR, Squire CJ, Gray EJ, Leupin W, Neidle S, Nucleic Acids Res. 1996 Dec 15;24(24):4882-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9017011 9017011]
[[Category: Clark, G R.]]
[[Category: Gray, E J.]]
[[Category: Leupin, W.]]
[[Category: Neidle, S.]]
[[Category: Squire, C J.]]
[[Category: B-dna]]
[[Category: Complexed with drug]]
[[Category: Double helix]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 02:28:07 2008''

Latest revision as of 08:38, 7 February 2024

META-HYDROXY ANALOGUE OF HOECHST 33258 ('HYDROXYL IN' CONFORMATION) BOUND TO D(CGCGAATTCGCG)2

302d, resolution 2.20Å

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