1y10: Difference between revisions

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{{Seed}}
[[Image:1y10.png|left|200px]]


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==Mycobacterial adenylyl cyclase Rv1264, holoenzyme, inhibited state==
The line below this paragraph, containing "STRUCTURE_1y10", creates the "Structure Box" on the page.
<StructureSection load='1y10' size='340' side='right'caption='[[1y10]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1y10]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y10 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y10 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_1y10| PDB=1y10 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y10 OCA], [https://pdbe.org/1y10 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y10 RCSB], [https://www.ebi.ac.uk/pdbsum/1y10 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y10 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Y1264_MYCTU Y1264_MYCTU] Catalyzes the formation of the second messenger cAMP.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y1/1y10_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y10 ConSurf].
<div style="clear:both"></div>


===Mycobacterial adenylyl cyclase Rv1264, holoenzyme, inhibited state===
==See Also==
 
*[[3D Adenylyl cyclase 3D structures|3D Adenylyl cyclase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_15890882}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 15890882 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_15890882}}
 
==About this Structure==
1Y10 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y10 OCA].
 
==Reference==
The structure of a pH-sensing mycobacterial adenylyl cyclase holoenzyme., Tews I, Findeisen F, Sinning I, Schultz A, Schultz JE, Linder JU, Science. 2005 May 13;308(5724):1020-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15890882 15890882]
[[Category: Adenylate cyclase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Single protein]]
[[Category: Findeisen F]]
[[Category: Findeisen, F.]]
[[Category: Linder JU]]
[[Category: Linder, J U.]]
[[Category: Schultz A]]
[[Category: Schultz, A.]]
[[Category: Schultz JE]]
[[Category: Schultz, J E.]]
[[Category: Sinning I]]
[[Category: Sinning, I.]]
[[Category: Tews I]]
[[Category: Tews, I.]]
[[Category: Adenylyl cyclase fold]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:05:14 2008''
Retrieved from "https://proteopedia.org/1y10"