2qvx: Difference between revisions

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{{Seed}}
[[Image:2qvx.png|left|200px]]


<!--
==4-Chlorobenzoyl-CoA Ligase/Synthetase, I303G mutation, bound to 3-Chlorobenzoate==
The line below this paragraph, containing "STRUCTURE_2qvx", creates the "Structure Box" on the page.
<StructureSection load='2qvx' size='340' side='right'caption='[[2qvx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2qvx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alcaligenes_sp._AL3007 Alcaligenes sp. AL3007]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QVX FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3BZ:3-CHLOROBENZOATE'>3BZ</scene></td></tr>
{{STRUCTURE_2qvx|  PDB=2qvx  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvx OCA], [https://pdbe.org/2qvx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qvx RCSB], [https://www.ebi.ac.uk/pdbsum/2qvx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qvx ProSAT]</span></td></tr>
 
</table>
===4-Chlorobenzoyl-CoA Ligase/Synthetase, I303G mutation, bound to 3-Chlorobenzoate===
== Function ==
 
[https://www.uniprot.org/uniprot/Q8GN86_9BURK Q8GN86_9BURK]
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_18027984}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 18027984 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qv/2qvx_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_18027984}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2QVX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Alcaligenes_sp. Alcaligenes sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVX OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qvx ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Rational redesign of the 4-chlorobenzoate binding site of 4-chlorobenzoate: coenzyme a ligase for expanded substrate range., Wu R, Reger AS, Cao J, Gulick AM, Dunaway-Mariano D, Biochemistry. 2007 Dec 18;46(50):14487-99. Epub 2007 Nov 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18027984 18027984]
</StructureSection>
[[Category: 4-chlorobenzoate--CoA ligase]]
[[Category: Alcaligenes sp. AL3007]]
[[Category: Alcaligenes sp.]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Cao J]]
[[Category: Cao, J.]]
[[Category: Dunaway-Mariano D]]
[[Category: Dunaway-Mariano, D.]]
[[Category: Gulick AM]]
[[Category: Gulick, A M.]]
[[Category: Reger AS]]
[[Category: Reger, A S.]]
[[Category: Wu R]]
[[Category: Wu, R.]]
[[Category: Acyl-coa ligase]]
[[Category: Adenylate-forming enzyme]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:15:15 2008''
Retrieved from "https://proteopedia.org/2qvx"