1p4g: Difference between revisions

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New page: left|200px<br /><applet load="1p4g" size="450" color="white" frame="true" align="right" spinBox="true" caption="1p4g, resolution 2.10Å" /> '''Crystal structure of...
 
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[[Image:1p4g.gif|left|200px]]<br /><applet load="1p4g" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1p4g, resolution 2.10&Aring;" />
'''Crystal structure of glycogen phosphorylase b in complex with C-(1-azido-alpha-D-glucopyranosyl)formamide'''<br />


==About this Structure==
==Crystal structure of glycogen phosphorylase b in complex with C-(1-azido-alpha-D-glucopyranosyl)formamide==
1P4G is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] with CGF and PLP as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1P4G OCA].  
<StructureSection load='1p4g' size='340' side='right'caption='[[1p4g]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1p4g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P4G FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CGF:C-(1-AZIDO-ALPHA-D-GLUCOPYRANOSYL)+FORMAMIDE'>CGF</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p4g OCA], [https://pdbe.org/1p4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p4g RCSB], [https://www.ebi.ac.uk/pdbsum/1p4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p4g ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PYGM_RABIT PYGM_RABIT] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p4/1p4g_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p4g ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Glycogen phosphorylase 3D structures|Glycogen phosphorylase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Phosphorylase]]
[[Category: Bischler N]]
[[Category: Single protein]]
[[Category: Chrysina ED]]
[[Category: Bischler, N.]]
[[Category: Gergely P]]
[[Category: Chrysina, E.D.]]
[[Category: Kosmopoulou MN]]
[[Category: Gergely, P.]]
[[Category: Leonidas DD]]
[[Category: Kosmopoulou, M.N.]]
[[Category: Nagy V]]
[[Category: Leonidas, D.D.]]
[[Category: Oikonomakos NG]]
[[Category: Nagy, V.]]
[[Category: Praly J-P]]
[[Category: Oikonomakos, N.G.]]
[[Category: Somsak L]]
[[Category: Praly, J.P.]]
[[Category: Zographos SE]]
[[Category: Somsak, L.]]
[[Category: Zographos, S.E.]]
[[Category: CGF]]
[[Category: PLP]]
[[Category: transferase]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 23:28:07 2007''
Retrieved from "https://proteopedia.org/1p4g"