1o7c: Difference between revisions

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{{Seed}}
[[Image:1o7c.png|left|200px]]


<!--
==Solution structure of the human TSG-6 Link module in the presence of a hyaluronan octasaccharide==
The line below this paragraph, containing "STRUCTURE_1o7c", creates the "Structure Box" on the page.
<StructureSection load='1o7c' size='340' side='right'caption='[[1o7c]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1o7c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O7C FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o7c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7c OCA], [https://pdbe.org/1o7c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o7c RCSB], [https://www.ebi.ac.uk/pdbsum/1o7c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o7c ProSAT]</span></td></tr>
{{STRUCTURE_1o7c|  PDB=1o7c  |  SCENE= }}
</table>
 
== Function ==
===SOLUTION STRUCTURE OF THE HUMAN TSG-6 LINK MODULE IN THE PRESENCE OF A HYALURONAN OCTASACCHARIDE===
[https://www.uniprot.org/uniprot/TSG6_HUMAN TSG6_HUMAN] Possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_12972412}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 12972412 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o7/1o7c_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_12972412}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1o7c ConSurf].
1O7C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7C OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
The link module from ovulation- and inflammation-associated protein TSG-6 changes conformation on hyaluronan binding., Blundell CD, Mahoney DJ, Almond A, DeAngelis PL, Kahmann JD, Teriete P, Pickford AR, Campbell ID, Day AJ, J Biol Chem. 2003 Dec 5;278(49):49261-70. Epub 2003 Sep 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12972412 12972412]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Blundell, C D.]]
[[Category: Blundell CD]]
[[Category: Campbell, I D.]]
[[Category: Campbell ID]]
[[Category: Day, A J.]]
[[Category: Day AJ]]
[[Category: Kahmann, J D.]]
[[Category: Kahmann JD]]
[[Category: Pickford, A R.]]
[[Category: Pickford AR]]
[[Category: Teriete, P.]]
[[Category: Teriete P]]
[[Category: Carbohydrate-binding domain]]
[[Category: Cell adhesion]]
[[Category: Glycoprotein]]
[[Category: Hyaluronan-binding domain]]
[[Category: Link module]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 04:55:28 2008''
Retrieved from "https://proteopedia.org/1o7c"