1mtc: Difference between revisions

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{{Seed}}
[[Image:1mtc.png|left|200px]]


<!--
==GLUTATHIONE TRANSFERASE MUTANT Y115F==
The line below this paragraph, containing "STRUCTURE_1mtc", creates the "Structure Box" on the page.
<StructureSection load='1mtc' size='340' side='right'caption='[[1mtc]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mtc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MTC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MTC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GPR:(9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE'>GPR</scene></td></tr>
{{STRUCTURE_1mtc| PDB=1mtc |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mtc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mtc OCA], [https://pdbe.org/1mtc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mtc RCSB], [https://www.ebi.ac.uk/pdbsum/1mtc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mtc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GSTM1_RAT GSTM1_RAT] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. The olfactory GST may be crucial for the acuity of the olfactory process.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mt/1mtc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mtc ConSurf].
<div style="clear:both"></div>


===GLUTATHIONE TRANSFERASE MUTANT Y115F===
==See Also==
 
*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
 
__TOC__
<!--  
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_12484753}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 12484753 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_12484753}}
 
==About this Structure==
1MTC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MTC OCA].
 
==Reference==
Local protein dynamics and catalysis: detection of segmental motion associated with rate-limiting product release by a glutathione transferase., Codreanu SG, Ladner JE, Xiao G, Stourman NV, Hachey DL, Gilliland GL, Armstrong RN, Biochemistry. 2002 Dec 24;41(51):15161-72. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12484753 12484753]
[[Category: Glutathione transferase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Armstrong RN]]
[[Category: Armstrong, R N.]]
[[Category: Gilliland GL]]
[[Category: Gilliland, G L.]]
[[Category: Ladner JE]]
[[Category: Ladner, J E.]]
[[Category: Xiao G]]
[[Category: Xiao, G.]]
[[Category: Glutathione transferase]]
[[Category: Protein catalysis]]
[[Category: Protein dynamic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:04:02 2008''

Latest revision as of 07:48, 14 February 2024

GLUTATHIONE TRANSFERASE MUTANT Y115F

1mtc, resolution 2.20Å

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