2hz5: Difference between revisions

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{{Seed}}
[[Image:2hz5.png|left|200px]]


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==Crystal structure of human dynein light chain Dnlc2A==
The line below this paragraph, containing "STRUCTURE_2hz5", creates the "Structure Box" on the page.
<StructureSection load='2hz5' size='340' side='right'caption='[[2hz5]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2hz5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HZ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HZ5 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene></td></tr>
{{STRUCTURE_2hz5| PDB=2hz5 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hz5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hz5 OCA], [https://pdbe.org/2hz5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hz5 RCSB], [https://www.ebi.ac.uk/pdbsum/2hz5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hz5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DLRB1_HUMAN DLRB1_HUMAN] Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hz/2hz5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hz5 ConSurf].
<div style="clear:both"></div>


===Crystal structure of human dynein light chain Dnlc2A===
==See Also==
 
*[[Dynein 3D structures|Dynein 3D structures]]
 
__TOC__
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{{ABSTRACT_PUBMED_16970917}}
 
==About this Structure==
2HZ5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HZ5 OCA].
 
==Reference==
Crystal structure of human dynein light chain Dnlc2A: structural insights into the interaction with IC74., Liu JF, Wang ZX, Wang XQ, Tang Q, An XM, Gui LL, Liang DC, Biochem Biophys Res Commun. 2006 Oct 27;349(3):1125-9. Epub 2006 Sep 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16970917 16970917]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: An, X M.]]
[[Category: An X-M]]
[[Category: Gui, L L.]]
[[Category: Gui L-L]]
[[Category: Liang, D C.]]
[[Category: Liang D-C]]
[[Category: Liu, J F.]]
[[Category: Liu J-F]]
[[Category: Tang, Q.]]
[[Category: Tang Q]]
[[Category: Wang, X Q.]]
[[Category: Wang X-Q]]
[[Category: Wang, Z X.]]
[[Category: Wang Z-X]]
[[Category: Dnlc2a]]
[[Category: Transport protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:58:52 2008''

Latest revision as of 13:52, 13 March 2024

Crystal structure of human dynein light chain Dnlc2A

2hz5, resolution 2.10Å

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