1s3m: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(9 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:1s3m.png|left|200px]]


<!--
==Structural and Functional Characterization of a Novel Archaeal Phosphodiesterase==
The line below this paragraph, containing "STRUCTURE_1s3m", creates the "Structure Box" on the page.
<StructureSection load='1s3m' size='340' side='right'caption='[[1s3m]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1s3m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S3M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S3M FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
{{STRUCTURE_1s3m|  PDB=1s3m  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s3m OCA], [https://pdbe.org/1s3m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s3m RCSB], [https://www.ebi.ac.uk/pdbsum/1s3m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s3m ProSAT], [https://www.topsan.org/Proteins/BSGC/1s3m TOPSAN]</span></td></tr>
 
</table>
===Structural and Functional Characterization of a Novel Archaeal Phosphodiesterase===
== Function ==
 
[https://www.uniprot.org/uniprot/P936_METJA P936_METJA] Shows phosphodiesterase activity, hydrolyzing phosphodiesters bonds in the artificial chromogenic substrates bis-p-nitrophenyl phosphate (bis-pNPP), and less efficiently thymidine 5'-monophosphate p-nitrophenyl ester (pNP-TMP) and p-nitrophenylphosphorylcholine (pNPPC). No catalytic activity was found toward cAMP or cGMP, nucleotides or phospholipase substrates such as phosphatidylcholine. The physiological substrate is unknown.
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_15128743}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 15128743 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s3/1s3m_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_15128743}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1S3M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S3M OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s3m ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii., Chen S, Yakunin AF, Kuznetsova E, Busso D, Pufan R, Proudfoot M, Kim R, Kim SH, J Biol Chem. 2004 Jul 23;279(30):31854-62. Epub 2004 May 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15128743 15128743]
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Single protein]]
[[Category: Busso D]]
[[Category: BSGC, Berkeley Structural Genomics Center.]]
[[Category: Chen S]]
[[Category: Busso, D.]]
[[Category: Jancrick J]]
[[Category: Chen, S.]]
[[Category: Kim R]]
[[Category: Jancrick, J.]]
[[Category: Kim S-H]]
[[Category: Kim, R.]]
[[Category: Kuznetsova E]]
[[Category: Kim, S H.]]
[[Category: Proudfoot M]]
[[Category: Kuznetsova, E.]]
[[Category: Yakunin AF]]
[[Category: Proudfoot, M.]]
[[Category: Yakunin, A F.]]
[[Category: Berkeley structural genomics center]]
[[Category: Bsgc structure funded by nih]]
[[Category: Di-metal-binding]]
[[Category: Phosphodiesterase/nuclease]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 06:18:04 2008''
Retrieved from "https://proteopedia.org/1s3m"