2ajh: Difference between revisions

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{{Seed}}
[[Image:2ajh.png|left|200px]]


<!--
==Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with methionine==
The line below this paragraph, containing "STRUCTURE_2ajh", creates the "Structure Box" on the page.
<StructureSection load='2ajh' size='340' side='right'caption='[[2ajh]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ajh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AJH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AJH FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr>
{{STRUCTURE_2ajh|  PDB=2ajh |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ajh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ajh OCA], [https://pdbe.org/2ajh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ajh RCSB], [https://www.ebi.ac.uk/pdbsum/2ajh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ajh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYL_ECOLI SYL_ECOLI]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aj/2ajh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ajh ConSurf].
<div style="clear:both"></div>


===Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with methionine===
==See Also==
 
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_16277600}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 16277600 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_16277600}}
 
==About this Structure==
2AJH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AJH OCA].
 
==Reference==
Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination., Liu Y, Liao J, Zhu B, Wang ED, Ding J, Biochem J. 2006 Mar 1;394(Pt 2):399-407. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16277600 16277600]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Leucine--tRNA ligase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Ding J]]
[[Category: Ding, J.]]
[[Category: Liao J]]
[[Category: Liao, J.]]
[[Category: Liu Y]]
[[Category: Liu, Y.]]
[[Category: Wang ED]]
[[Category: Wang, E D.]]
[[Category: Zhu B]]
[[Category: Zhu, B.]]
[[Category: Editing domain]]
[[Category: Leucyl-trna synthetase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 06:57:18 2008''

Latest revision as of 13:41, 13 March 2024

Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with methionine

2ajh, resolution 2.40Å

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