3b60: Difference between revisions

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{{Seed}}
[[Image:3b60.png|left|200px]]


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==Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP, higher resolution form==
The line below this paragraph, containing "STRUCTURE_3b60", creates the "Structure Box" on the page.
<StructureSection load='3b60' size='340' side='right'caption='[[3b60]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3b60]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B60 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B60 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
{{STRUCTURE_3b60|  PDB=3b60  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b60 OCA], [https://pdbe.org/3b60 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b60 RCSB], [https://www.ebi.ac.uk/pdbsum/3b60 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b60 ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP, higher resolution form===
== Function ==
 
[https://www.uniprot.org/uniprot/MSBA_SALTY MSBA_SALTY] Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/3b60_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_18024585}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
3B60 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B60 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b60 ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Flexibility in the ABC transporter MsbA: Alternating access with a twist., Ward A, Reyes CL, Yu J, Roth CB, Chang G, Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):19005-10. Epub 2007 Nov 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18024585 18024585]
</StructureSection>
[[Category: Salmonella typhimurium]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Chang, G.]]
[[Category: Chang G]]
[[Category: Reyes, C L.]]
[[Category: Reyes CL]]
[[Category: Roth, C B.]]
[[Category: Roth CB]]
[[Category: Ward, A.]]
[[Category: Ward A]]
[[Category: Yu, J.]]
[[Category: Yu J]]
[[Category: Abc transporter]]
[[Category: Atp-binding]]
[[Category: Hydrolase]]
[[Category: Inner membrane]]
[[Category: Lipid flippase]]
[[Category: Lipid transport]]
[[Category: Membrane]]
[[Category: Membrane protein]]
[[Category: Msba]]
[[Category: Nucleotide-binding]]
[[Category: Transmembrane]]
 
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Retrieved from "https://proteopedia.org/3b60"