1sg4: Difference between revisions

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{{Seed}}
[[Image:1sg4.png|left|200px]]


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==Crystal structure of human mitochondrial delta3-delta2-enoyl-CoA isomerase==
The line below this paragraph, containing "STRUCTURE_1sg4", creates the "Structure Box" on the page.
<StructureSection load='1sg4' size='340' side='right'caption='[[1sg4]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1sg4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SG4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO8:OCTANOYL-COENZYME+A'>CO8</scene></td></tr>
{{STRUCTURE_1sg4|  PDB=1sg4  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sg4 OCA], [https://pdbe.org/1sg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sg4 RCSB], [https://www.ebi.ac.uk/pdbsum/1sg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sg4 ProSAT]</span></td></tr>
 
</table>
===Crystal structure of human mitochondrial delta3-delta2-enoyl-CoA isomerase===
== Function ==
 
[https://www.uniprot.org/uniprot/ECI1_HUMAN ECI1_HUMAN] Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sg/1sg4_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_15351645}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1SG4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SG4 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sg4 ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
The 1.3 A crystal structure of human mitochondrial Delta3-Delta2-enoyl-CoA isomerase shows a novel mode of binding for the fatty acyl group., Partanen ST, Novikov DK, Popov AN, Mursula AM, Hiltunen JK, Wierenga RK, J Mol Biol. 2004 Sep 24;342(4):1197-208. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15351645 15351645]
</StructureSection>
[[Category: Dodecenoyl-CoA isomerase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Hiltunen, J K.]]
[[Category: Hiltunen JK]]
[[Category: Mursula, A M.]]
[[Category: Mursula AM]]
[[Category: Novikov, D K.]]
[[Category: Novikov DK]]
[[Category: Partanen, S T.]]
[[Category: Partanen ST]]
[[Category: Popov, A N.]]
[[Category: Popov AN]]
[[Category: Wierenga, R K.]]
[[Category: Wierenga RK]]
[[Category: Crotonase fold]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:11:03 2008''