1s2m: Difference between revisions

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{{Seed}}
[[Image:1s2m.png|left|200px]]


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==Crystal Structure of the DEAD box protein Dhh1p==
The line below this paragraph, containing "STRUCTURE_1s2m", creates the "Structure Box" on the page.
<StructureSection load='1s2m' size='340' side='right'caption='[[1s2m]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1s2m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S2M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S2M FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s2m OCA], [https://pdbe.org/1s2m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s2m RCSB], [https://www.ebi.ac.uk/pdbsum/1s2m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s2m ProSAT]</span></td></tr>
{{STRUCTURE_1s2m| PDB=1s2m |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/DHH1_YEAST DHH1_YEAST] ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export. Required for sporulation.<ref>PMID:9504907</ref> <ref>PMID:11780629</ref> <ref>PMID:12032091</ref> <ref>PMID:11696541</ref> <ref>PMID:12930949</ref> <ref>PMID:12730603</ref> <ref>PMID:15166134</ref> <ref>PMID:15703442</ref> <ref>PMID:15706350</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s2/1s2m_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s2m ConSurf].
<div style="clear:both"></div>


===Crystal Structure of the DEAD box protein Dhh1p===
==See Also==
 
*[[Helicase 3D structures|Helicase 3D structures]]
 
== References ==
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The line below this paragraph, {{ABSTRACT_PUBMED_15987810}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15987810 is the PubMed ID number.
</StructureSection>
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_15987810}}
 
==About this Structure==
1S2M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S2M OCA].
 
==Reference==
Crystal structure and functional analysis of DEAD-box protein Dhh1p., Cheng Z, Coller J, Parker R, Song H, RNA. 2005 Aug;11(8):1258-70. Epub 2005 Jun 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15987810 15987810]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Cheng Z]]
[[Category: Cheng, Z.]]
[[Category: Song H]]
[[Category: Song, H.]]
[[Category: Atp-binding]]
[[Category: Helicase]]
[[Category: Rna-binding]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:32:32 2008''
Retrieved from "https://proteopedia.org/1s2m"