2ews: Difference between revisions

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{{Seed}}
[[Image:2ews.png|left|200px]]


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==Crystal structure of S.aureus pantothenate kinase==
The line below this paragraph, containing "STRUCTURE_2ews", creates the "Structure Box" on the page.
<StructureSection load='2ews' size='340' side='right'caption='[[2ews]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ews]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MSSA476 Staphylococcus aureus subsp. aureus MSSA476]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EWS FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_2ews| PDB=2ews |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ews FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ews OCA], [https://pdbe.org/2ews PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ews RCSB], [https://www.ebi.ac.uk/pdbsum/2ews PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ews ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/COAW_STAAS COAW_STAAS] Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.<ref>PMID:16905099</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/2ews_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ews ConSurf].
<div style="clear:both"></div>


===Crystal structure of S.aureus pantothenate kinase===
==See Also==
 
*[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]]
 
== References ==
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<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_16905099}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 16905099 is the PubMed ID number.
</StructureSection>
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_16905099}}
[[Category: Staphylococcus aureus subsp. aureus MSSA476]]
 
[[Category: Hong BS]]
==About this Structure==
[[Category: Park HW]]
2EWS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EWS OCA].
 
==Reference==
Prokaryotic type II and type III pantothenate kinases: The same monomer fold creates dimers with distinct catalytic properties., Hong BS, Yun MK, Zhang YM, Chohnan S, Rock CO, White SW, Jackowski S, Park HW, Leonardi R, Structure. 2006 Aug;14(8):1251-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16905099 16905099]
[[Category: Pantothenate kinase]]
[[Category: Single protein]]
[[Category: Staphylococcus aureus]]
[[Category: Hong, B S.]]
[[Category: Park, H W.]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Pank]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:04:45 2008''