1s98: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(9 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:1s98.png|left|200px]]


<!--
==E.coli IscA crystal structure to 2.3 A==
The line below this paragraph, containing "STRUCTURE_1s98", creates the "Structure Box" on the page.
<StructureSection load='1s98' size='340' side='right'caption='[[1s98]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1s98]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S98 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S98 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s98 OCA], [https://pdbe.org/1s98 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s98 RCSB], [https://www.ebi.ac.uk/pdbsum/1s98 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s98 ProSAT]</span></td></tr>
{{STRUCTURE_1s98|  PDB=1s98  |  SCENE=  }}
</table>
 
== Function ==
===E.coli IscA crystal structure to 2.3 A===
[https://www.uniprot.org/uniprot/ISCA_ECOLI ISCA_ECOLI] Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.[HAMAP-Rule:MF_01429]
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_15050828}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 15050828 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s9/1s98_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_15050828}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s98 ConSurf].
1S98 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S98 OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
Crystal structure of IscA, an iron-sulfur cluster assembly protein from Escherichia coli., Cupp-Vickery JR, Silberg JJ, Ta DT, Vickery LE, J Mol Biol. 2004 Apr 16;338(1):127-37. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15050828 15050828]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Cupp-Vickery, J R.]]
[[Category: Cupp-Vickery JR]]
[[Category: Silberg, J J.]]
[[Category: Silberg JJ]]
[[Category: Ta, D T.]]
[[Category: Ta DT]]
[[Category: Vickery, L E.]]
[[Category: Vickery LE]]
[[Category: Fe-s cluster]]
[[Category: Iron]]
[[Category: Isc]]
[[Category: Isca]]
[[Category: Sulfur]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:05:43 2008''
Retrieved from "https://proteopedia.org/1s98"