2h2e: Difference between revisions

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{{Seed}}
[[Image:2h2e.png|left|200px]]


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==Structure of Rubisco LSMT bound to AzaAdoMet and Lysine==
The line below this paragraph, containing "STRUCTURE_2h2e", creates the "Structure Box" on the page.
<StructureSection load='2h2e' size='340' side='right'caption='[[2h2e]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2h2e]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pisum_sativum Pisum sativum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H2E FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=SA8:S-5-AZAMETHIONINE-5-DEOXYADENOSINE'>SA8</scene></td></tr>
{{STRUCTURE_2h2e| PDB=2h2e |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h2e OCA], [https://pdbe.org/2h2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h2e RCSB], [https://www.ebi.ac.uk/pdbsum/2h2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h2e ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RBCMT_PEA RBCMT_PEA] Methylates 'Lys-14' of the large subunit of RuBisCO. Can also use with lower efficiency chloroplastic fructose-bisphosphate aldolases and gamma-tocopherol methyltransferase as substrates, but not a cytosolic aldolase.<ref>PMID:22547063</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h2/2h2e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2h2e ConSurf].
<div style="clear:both"></div>


===Structure of Rubisco LSMT bound to AzaAdoMet and Lysine===
==See Also==
 
*[[RuBisCO 3D structures|RuBisCO 3D structures]]
 
== References ==
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(as it appears on PubMed at http://www.pubmed.gov), where 16682405 is the PubMed ID number.
</StructureSection>
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_16682405}}
 
==About this Structure==
2H2E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pisum_sativum Pisum sativum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H2E OCA].
 
==Reference==
Catalytic roles for carbon-oxygen hydrogen bonding in SET domain lysine methyltransferases., Couture JF, Hauk G, Thompson MJ, Blackburn GM, Trievel RC, J Biol Chem. 2006 Jul 14;281(28):19280-7. Epub 2006 May 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16682405 16682405]
[[Category: Pisum sativum]]
[[Category: Pisum sativum]]
[[Category: Single protein]]
[[Category: Couture JF]]
[[Category: Couture, J F.]]
[[Category: Hauk G]]
[[Category: Hauk, G.]]
[[Category: Trievel RC]]
[[Category: Trievel, R C.]]
[[Category: Protein lysine methyltransferase]]
[[Category: Set domain]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:11:49 2008''