2a6l: Difference between revisions

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{{Seed}}
[[Image:2a6l.png|left|200px]]


<!--
==Dihydrodipicolinate synthase (E. coli)- mutant R138H==
The line below this paragraph, containing "STRUCTURE_2a6l", creates the "Structure Box" on the page.
<StructureSection load='2a6l' size='340' side='right'caption='[[2a6l]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2a6l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A6L FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
{{STRUCTURE_2a6l| PDB=2a6l |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a6l OCA], [https://pdbe.org/2a6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a6l RCSB], [https://www.ebi.ac.uk/pdbsum/2a6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a6l ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DAPA_ECOLI DAPA_ECOLI] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).<ref>PMID:20503968</ref> <ref>PMID:8993314</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a6/2a6l_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a6l ConSurf].
<div style="clear:both"></div>


===Dihydrodipicolinate synthase (E. coli)- mutant R138H===
==See Also==
 
*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_16185069}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 16185069 is the PubMed ID number.
</StructureSection>
-->
{{ABSTRACT_PUBMED_16185069}}
 
==About this Structure==
2A6L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A6L OCA].
 
==Reference==
Role of arginine 138 in the catalysis and regulation of Escherichia coli dihydrodipicolinate synthase., Dobson RC, Devenish SR, Turner LA, Clifford VR, Pearce FG, Jameson GB, Gerrard JA, Biochemistry. 2005 Oct 4;44(39):13007-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16185069 16185069]
[[Category: Dihydrodipicolinate synthase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Clifford, V R.]]
[[Category: Clifford VR]]
[[Category: Devenish, S R.]]
[[Category: Devenish SR]]
[[Category: Dobson, R C.]]
[[Category: Dobson RC]]
[[Category: Gerrard, J A.]]
[[Category: Gerrard JA]]
[[Category: Jameson, G B.]]
[[Category: Jameson GB]]
[[Category: Pearce, F G.]]
[[Category: Pearce FG]]
[[Category: Turner, L A.]]
[[Category: Turner LA]]
[[Category: Beta-alpha-barrel]]
[[Category: Dihydrodipicolinate synthase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:54:14 2008''
Retrieved from "https://proteopedia.org/2a6l"