3bc9: Difference between revisions

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{{Seed}}
[[Image:3bc9.png|left|200px]]


<!--
==Alpha-amylase B in complex with acarbose==
The line below this paragraph, containing "STRUCTURE_3bc9", creates the "Structure Box" on the page.
<StructureSection load='3bc9' size='340' side='right'caption='[[3bc9]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3bc9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halothermothrix_orenii_H_168 Halothermothrix orenii H 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BC9 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AC1:6-METHYL-5-(4,5,6-TRIHYDROXY-3-HYDROXYMETHYL-CYCLOHEX-2-ENYLAMINO)-TETRAHYDRO-PYRAN-2,3,4-TRIOL'>AC1</scene>, <scene name='pdbligand=ACI:6-AMINO-4-HYDROXYMETHYL-CYCLOHEX-4-ENE-1,2,3-TRIOL'>ACI</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G6D:6-DEOXY-ALPHA-D-GLUCOSE'>G6D</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GLD:4,6-DIDEOXYGLUCOSE'>GLD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PRD_900007:alpha-acarbose'>PRD_900007</scene></td></tr>
{{STRUCTURE_3bc9| PDB=3bc9 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bc9 OCA], [https://pdbe.org/3bc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bc9 RCSB], [https://www.ebi.ac.uk/pdbsum/3bc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bc9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B8CZ54_HALOH B8CZ54_HALOH]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bc/3bc9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bc9 ConSurf].
<div style="clear:both"></div>


===Alpha-amylase B in complex with acarbose===
==See Also==
 
*[[Amylase 3D structures|Amylase 3D structures]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_18387632}}, adds the Publication Abstract to the page
[[Category: Halothermothrix orenii H 168]]
(as it appears on PubMed at http://www.pubmed.gov), where 18387632 is the PubMed ID number.
[[Category: Large Structures]]
-->
[[Category: Divne C]]
{{ABSTRACT_PUBMED_18387632}}
[[Category: Mijts BN]]
 
[[Category: Patel BKC]]
==About this Structure==
[[Category: Swaminathan K]]
3BC9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Halothermothrix_orenii Halothermothrix orenii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BC9 OCA].
[[Category: Tan T-C]]
 
==Reference==
Crystal structure of the polyextremophilic alpha-amylase AmyB from Halothermothrix orenii: details of a productive enzyme-substrate complex and an N domain with a role in binding raw starch., Tan TC, Mijts BN, Swaminathan K, Patel BK, Divne C, J Mol Biol. 2008 May 9;378(4):850-68. Epub 2008 Feb 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18387632 18387632]
[[Category: Alpha-amylase]]
[[Category: Halothermothrix orenii]]
[[Category: Single protein]]
[[Category: Divne, C.]]
[[Category: Mijts, B N.]]
[[Category: Patel, B K.C.]]
[[Category: Swaminathan, K.]]
[[Category: Tan, T C.]]
[[Category: Acarbose]]
[[Category: Alpha-amylase]]
[[Category: Halophilic]]
[[Category: Hydrolase]]
[[Category: N domain]]
[[Category: Raw starch binding]]
[[Category: Thermostable]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:58:58 2008''

Latest revision as of 14:03, 13 March 2024

Alpha-amylase B in complex with acarbose

3bc9, resolution 1.35Å

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