2pmc: Difference between revisions

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{{Seed}}
[[Image:2pmc.png|left|200px]]


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==Crystal Structure of CheY-Mg(2+) in Complex with CheZ(C15) Peptide solved from a P1 Crystal==
The line below this paragraph, containing "STRUCTURE_2pmc", creates the "Structure Box" on the page.
<StructureSection load='2pmc' size='340' side='right'caption='[[2pmc]], [[Resolution|resolution]] 2.69&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2pmc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PMC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PMC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.688&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_2pmc| PDB=2pmc |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pmc OCA], [https://pdbe.org/2pmc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pmc RCSB], [https://www.ebi.ac.uk/pdbsum/2pmc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pmc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CHEY_SALTY CHEY_SALTY] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Shows autophosphatase activity which is enhanced by CheZ.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pm/2pmc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pmc ConSurf].
<div style="clear:both"></div>


===Crystal Structure of CheY-Mg(2+) in Complex with CheZ(C15) Peptide solved from a P1 Crystal===
==See Also==
 
*[[Chemotaxis protein 3D structures|Chemotaxis protein 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_18083806}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 18083806 is the PubMed ID number.
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Guhaniyogi J]]
{{ABSTRACT_PUBMED_18083806}}
[[Category: Stock AM]]
 
==About this Structure==
2PMC is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PMC OCA].
 
==Reference==
Interaction of CheY with the C-terminal peptide of CheZ., Guhaniyogi J, Wu T, Patel SS, Stock AM, J Bacteriol. 2008 Feb;190(4):1419-28. Epub 2007 Dec 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18083806 18083806]
[[Category: Protein complex]]
[[Category: Salmonella typhimurium]]
[[Category: Guhaniyogi, J.]]
[[Category: Stock, A M.]]
[[Category: Chemotaxis]]
[[Category: Chey-chez peptide complex]]
[[Category: Signaling protein]]
 
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