1mr7: Difference between revisions

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{{Seed}}
[[Image:1mr7.png|left|200px]]


<!--
==Crystal Structure of Streptogramin A Acetyltransferase==
The line below this paragraph, containing "STRUCTURE_1mr7", creates the "Structure Box" on the page.
<StructureSection load='1mr7' size='340' side='right'caption='[[1mr7]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mr7]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecium Enterococcus faecium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MR7 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mr7 OCA], [https://pdbe.org/1mr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mr7 RCSB], [https://www.ebi.ac.uk/pdbsum/1mr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mr7 ProSAT]</span></td></tr>
{{STRUCTURE_1mr7|  PDB=1mr7  |  SCENE=  }}
</table>
 
== Function ==
===Crystal Structure of Streptogramin A Acetyltransferase===
[https://www.uniprot.org/uniprot/VATD_ENTFC VATD_ENTFC] Inactivates the A compounds of streptogramin antibiotics by acetylation, thus providing resistance to these antibiotics.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_12771141}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 12771141 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mr/1mr7_consurf.spt"</scriptWhenChecked>
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    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_12771141}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mr7 ConSurf].
1MR7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecium Enterococcus faecium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MR7 OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
Structural basis of Synercid (quinupristin-dalfopristin) resistance in Gram-positive bacterial pathogens., Kehoe LE, Snidwongse J, Courvalin P, Rafferty JB, Murray IA, J Biol Chem. 2003 Aug 8;278(32):29963-70. Epub 2003 May 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12771141 12771141]
[[Category: Enterococcus faecium]]
[[Category: Enterococcus faecium]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Courvalin, P.]]
[[Category: Courvalin P]]
[[Category: Kehoe, L E.]]
[[Category: Kehoe LE]]
[[Category: Murray, I A.]]
[[Category: Murray IA]]
[[Category: Rafferty, J B.]]
[[Category: Rafferty JB]]
[[Category: Snidwongse, J.]]
[[Category: Snidwongse J]]
[[Category: Left-handed parallel beta-helix domain]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:24:49 2008''

Latest revision as of 13:27, 13 March 2024

Crystal Structure of Streptogramin A Acetyltransferase

1mr7, resolution 1.80Å

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