1q2l: Difference between revisions

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New page: left|200px<br /><applet load="1q2l" size="450" color="white" frame="true" align="right" spinBox="true" caption="1q2l, resolution 2.2Å" /> '''Crystal Structure of ...
 
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[[Image:1q2l.gif|left|200px]]<br /><applet load="1q2l" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1q2l, resolution 2.2&Aring;" />
'''Crystal Structure of pitrilysin'''<br />


==About this Structure==
==Crystal Structure of pitrilysin==
1Q2L is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with ZN and PT as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Pitrilysin Pitrilysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.55 3.4.24.55] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1Q2L OCA].  
<StructureSection load='1q2l' size='340' side='right'caption='[[1q2l]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
[[Category: Escherichia coli]]
== Structural highlights ==
[[Category: Pitrilysin]]
<table><tr><td colspan='2'>[[1q2l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._W3110 Escherichia coli str. K-12 substr. W3110]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q2L FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
[[Category: Fernandez-Catalan, C.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Jozic, D.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q2l OCA], [https://pdbe.org/1q2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q2l RCSB], [https://www.ebi.ac.uk/pdbsum/1q2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q2l ProSAT]</span></td></tr>
[[Category: Maskos, K.]]
</table>
[[Category: PT]]
== Function ==
[[Category: ZN]]
[https://www.uniprot.org/uniprot/PTRA_ECOLI PTRA_ECOLI] Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.
[[Category: hydrolase]]
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 00:20:02 2007''
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q2/1q2l_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q2l ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Escherichia coli str. K-12 substr. W3110]]
[[Category: Large Structures]]
[[Category: Fernandez-Catalan C]]
[[Category: Jozic D]]
[[Category: Maskos K]]