2vkx: Difference between revisions

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{{Seed}}
[[Image:2vkx.png|left|200px]]


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==Human NCAM, FN3 domains 1 and 2, M610R mutant==
The line below this paragraph, containing "STRUCTURE_2vkx", creates the "Structure Box" on the page.
<StructureSection load='2vkx' size='340' side='right'caption='[[2vkx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2vkx]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VKX FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_2vkx|  PDB=2vkx  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vkx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vkx OCA], [https://pdbe.org/2vkx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vkx RCSB], [https://www.ebi.ac.uk/pdbsum/2vkx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vkx ProSAT]</span></td></tr>
 
</table>
===HUMAN NCAM, FN3 DOMAINS 1 AND 2, M610R MUTANT===
== Function ==
 
[https://www.uniprot.org/uniprot/NCAM1_HUMAN NCAM1_HUMAN] This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_18261743}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 18261743 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vk/2vkx_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_18261743}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2VKX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKX OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vkx ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Structure of the Tandem Fibronectin Type 3 Domains of Neural Cell Adhesion Molecule., Carafoli F, Saffell JL, Hohenester E, J Mol Biol. 2008 Jan 17;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18261743 18261743]
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Carafoli, F.]]
[[Category: Carafoli F]]
[[Category: Hohenester, E.]]
[[Category: Hohenester E]]
[[Category: Saffell, J L.]]
[[Category: Saffell JL]]
[[Category: Adhesion receptor]]
[[Category: Cell adhesion]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:49:40 2008''