3cl3: Difference between revisions

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{{Seed}}
[[Image:3cl3.png|left|200px]]


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==Crystal Structure of a vFLIP-IKKgamma complex: Insights into viral activation of the IKK signalosome==
The line below this paragraph, containing "STRUCTURE_3cl3", creates the "Structure Box" on the page.
<StructureSection load='3cl3' size='340' side='right'caption='[[3cl3]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3cl3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_8 Human gammaherpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CL3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CL3 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cl3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cl3 OCA], [https://pdbe.org/3cl3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cl3 RCSB], [https://www.ebi.ac.uk/pdbsum/3cl3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cl3 ProSAT]</span></td></tr>
{{STRUCTURE_3cl3|  PDB=3cl3  |  SCENE=  }}
</table>
 
== Function ==
===Crystal Structure of a vFLIP-IKKgamma complex: Insights into viral activation of the IKK signalosome===
[https://www.uniprot.org/uniprot/Q76RF1_HHV8 Q76RF1_HHV8]
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 18538660 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cl/3cl3_consurf.spt"</scriptWhenChecked>
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    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_18538660}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cl3 ConSurf].
3CL3 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_herpesvirus_8 Human herpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CL3 OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome., Bagneris C, Ageichik AV, Cronin N, Wallace B, Collins M, Boshoff C, Waksman G, Barrett T, Mol Cell. 2008 Jun 6;30(5):620-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18538660 18538660]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Human herpesvirus 8]]
[[Category: Human gammaherpesvirus 8]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Ageichik, A V.]]
[[Category: Ageichik AV]]
[[Category: Bagneris, C.]]
[[Category: Bagneris C]]
[[Category: Barrett, T.]]
[[Category: Barrett T]]
[[Category: Boshoff, C.]]
[[Category: Boshoff C]]
[[Category: Cronin, N.]]
[[Category: Cronin N]]
[[Category: Waksman, G.]]
[[Category: Waksman G]]
[[Category: Coiled coil]]
[[Category: Coiled-coil]]
[[Category: Cytoplasm]]
[[Category: Death effector domain]]
[[Category: Disease mutation]]
[[Category: Ectodermal dysplasia]]
[[Category: Host-virus interaction]]
[[Category: Nucleus]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Viral protein/signaling protein complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:35:48 2008''
Retrieved from "https://proteopedia.org/3cl3"