2ov4: Difference between revisions

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{{Seed}}
[[Image:2ov4.png|left|200px]]


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==Crystal structure of B. stearothermophilus tryptophanyl tRNA synthetase in complex with adenosine tetraphosphate==
The line below this paragraph, containing "STRUCTURE_2ov4", creates the "Structure Box" on the page.
<StructureSection load='2ov4' size='340' side='right'caption='[[2ov4]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ov4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OV4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OV4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANL:ANILINE'>ANL</scene>, <scene name='pdbligand=AQP:ADENOSINE-5-TETRAPHOSPHATE'>AQP</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
{{STRUCTURE_2ov4|  PDB=2ov4 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ov4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ov4 OCA], [https://pdbe.org/2ov4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ov4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ov4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ov4 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYW_GEOSE SYW_GEOSE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ov/2ov4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ov4 ConSurf].
<div style="clear:both"></div>


===Crystal structure of B. stearothermophilus tryptophanyl tRNA synthetase in complex with adenosine tetraphosphate===
==See Also==
 
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_17428498}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 17428498 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17428498}}
 
==About this Structure==
2OV4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OV4 OCA].
 
==Reference==
Crystal structure of tryptophanyl-tRNA synthetase complexed with adenosine-5' tetraphosphate: evidence for distributed use of catalytic binding energy in amino acid activation by class I aminoacyl-tRNA synthetases., Retailleau P, Weinreb V, Hu M, Carter CW Jr, J Mol Biol. 2007 May 25;369(1):108-28. Epub 2007 Mar 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17428498 17428498]
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Tryptophan--tRNA ligase]]
[[Category: Carter Jr CW]]
[[Category: Jr., C W.Carter.]]
[[Category: Retailleau P]]
[[Category: Retailleau, P.]]
[[Category: Aminoacyl-trna synthetase]]
[[Category: Nucleotide binding site]]
[[Category: Rossmann fold]]
[[Category: Transition state analog inhibitor]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:04:58 2008''