2gvw: Difference between revisions

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{{Seed}}
[[Image:2gvw.png|left|200px]]


<!--
==Structure of diisopropyl fluorophosphatase (DFPase) holoenzyme (RT)==
The line below this paragraph, containing "STRUCTURE_2gvw", creates the "Structure Box" on the page.
<StructureSection load='2gvw' size='340' side='right'caption='[[2gvw]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2gvw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Loligo_vulgaris Loligo vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GVW FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_2gvw| PDB=2gvw |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvw OCA], [https://pdbe.org/2gvw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gvw RCSB], [https://www.ebi.ac.uk/pdbsum/2gvw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gvw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DFPA_LOLVU DFPA_LOLVU] Biological function and substrate unknown. However, it is capable of acting on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including nerve gases).<ref>PMID:15966726</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/2gvw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gvw ConSurf].
<div style="clear:both"></div>


===Structure of diisopropyl fluorophosphatase (DFPase) holoenzyme (RT)===
==See Also==
 
*[[Phosphotriesterase 3D structures|Phosphotriesterase 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_17002369}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 17002369 is the PubMed ID number.
</StructureSection>
-->
[[Category: Large Structures]]
{{ABSTRACT_PUBMED_17002369}}
 
==About this Structure==
2GVW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Loligo_vulgaris Loligo vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVW OCA].
 
==Reference==
Binding of a designed substrate analogue to diisopropyl fluorophosphatase: implications for the phosphotriesterase mechanism., Blum MM, Lohr F, Richardt A, Ruterjans H, Chen JC, J Am Chem Soc. 2006 Oct 4;128(39):12750-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17002369 17002369]
[[Category: Diisopropyl-fluorophosphatase]]
[[Category: Loligo vulgaris]]
[[Category: Loligo vulgaris]]
[[Category: Single protein]]
[[Category: Blum MM]]
[[Category: Blum, M M.]]
[[Category: Chen JCH]]
[[Category: Chen, J C.H.]]
[[Category: Beta-propeller]]
[[Category: Phosphotriesterase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:25:31 2008''

Latest revision as of 09:30, 14 February 2024

Structure of diisopropyl fluorophosphatase (DFPase) holoenzyme (RT)

2gvw, resolution 1.86Å

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