2dz7: Difference between revisions

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{{Seed}}
[[Image:2dz7.png|left|200px]]


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==DNA Octaplex Formation with an I-Motif of A-Quartets: The Revised Crystal Structure of d(GCGAAAGC)==
The line below this paragraph, containing "STRUCTURE_2dz7", creates the "Structure Box" on the page.
<StructureSection load='2dz7' size='340' side='right'caption='[[2dz7]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2dz7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DZ7 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_2dz7|  PDB=2dz7  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dz7 OCA], [https://pdbe.org/2dz7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dz7 RCSB], [https://www.ebi.ac.uk/pdbsum/2dz7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dz7 ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The crystal structure of the tetragonal form of d(gcGAAAgc) has been revised and reasonably refined including the disordered residues. The two DNA strands form a base-intercalated duplex, and the four duplexes are assembled according to the crystallographic 222 symmetry to form an octaplex. In the central region, the eight strands are associated by I-motif of double A-quartets. Furthermore, eight hydrated-magnesium cations link the four duplexes to support the octaplex formation. Based on these structural features, a proposal that folding of d(GAAA)n, found in the non-coding region of genomes, into an octaplex can induce slippage during replication to facilitate length polymorphism is presented.


===DNA Octaplex Formation with an I-Motif of A-Quartets: The Revised Crystal Structure of d(GCGAAAGC)===
DNA octaplex formation with an I-motif of water-mediated A-quartets: reinterpretation of the crystal structure of d(GCGAAAGC).,Sato Y, Mitomi K, Sunami T, Kondo J, Takenaka A J Biochem. 2006 Dec;140(6):759-62. Epub 2006 Oct 24. PMID:17062599<ref>PMID:17062599</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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The line below this paragraph, {{ABSTRACT_PUBMED_17062599}}, adds the Publication Abstract to the page
<div class="pdbe-citations 2dz7" style="background-color:#fffaf0;"></div>
(as it appears on PubMed at http://www.pubmed.gov), where 17062599 is the PubMed ID number.
== References ==
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<references/>
{{ABSTRACT_PUBMED_17062599}}
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</StructureSection>
==About this Structure==
[[Category: Large Structures]]
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZ7 OCA].
[[Category: Kondo J]]
 
[[Category: Mitomi K]]
==Reference==
[[Category: Sato Y]]
DNA octaplex formation with an I-motif of water-mediated A-quartets: reinterpretation of the crystal structure of d(GCGAAAGC)., Sato Y, Mitomi K, Sunami T, Kondo J, Takenaka A, J Biochem. 2006 Dec;140(6):759-62. Epub 2006 Oct 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17062599 17062599]
[[Category: Sumani T]]
[[Category: Kondo, J.]]
[[Category: Takenaka A]]
[[Category: Mitomi, K.]]
[[Category: Sato, Y.]]
[[Category: Sumani, T.]]
[[Category: Takenaka, A.]]
[[Category: A-quartet]]
[[Category: Dna octaplex]]
[[Category: Non-coding dna]]
[[Category: Vntr]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:52:29 2008''

Latest revision as of 18:43, 20 September 2023

DNA Octaplex Formation with an I-Motif of A-Quartets: The Revised Crystal Structure of d(GCGAAAGC)

2dz7, resolution 1.60Å

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