1mul: Difference between revisions

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{{Seed}}
[[Image:1mul.png|left|200px]]


<!--
==Crystal structure of the E. coli HU alpha2 protein==
The line below this paragraph, containing "STRUCTURE_1mul", creates the "Structure Box" on the page.
<StructureSection load='1mul' size='340' side='right'caption='[[1mul]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mul]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MUL FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mul FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mul OCA], [https://pdbe.org/1mul PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mul RCSB], [https://www.ebi.ac.uk/pdbsum/1mul PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mul ProSAT]</span></td></tr>
{{STRUCTURE_1mul|  PDB=1mul  |  SCENE=  }}
</table>
 
== Function ==
===Crystal structure of the E. coli HU alpha2 protein===
[https://www.uniprot.org/uniprot/DBHA_ECOLI DBHA_ECOLI] Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_12875839}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 12875839 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mu/1mul_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_12875839}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mul ConSurf].
1MUL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUL OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
Evidence of a thermal unfolding dimeric intermediate for the Escherichia coli histone-like HU proteins: thermodynamics and structure., Ramstein J, Hervouet N, Coste F, Zelwer C, Oberto J, Castaing B, J Mol Biol. 2003 Aug 1;331(1):101-21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12875839 12875839]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Castaing, B.]]
[[Category: Castaing B]]
[[Category: Coste, F.]]
[[Category: Coste F]]
[[Category: Hervouet, N.]]
[[Category: Hervouet N]]
[[Category: Oberto, J.]]
[[Category: Oberto J]]
[[Category: Ramstein, J.]]
[[Category: Ramstein J]]
[[Category: Zelwer, C.]]
[[Category: Zelwer C]]
[[Category: Histone-like]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:04:55 2008''
Retrieved from "https://proteopedia.org/1mul"