1p15: Difference between revisions

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{{Seed}}
[[Image:1p15.png|left|200px]]


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==Crystal structure of the D2 domain of RPTPa==
The line below this paragraph, containing "STRUCTURE_1p15", creates the "Structure Box" on the page.
<StructureSection load='1p15' size='340' side='right'caption='[[1p15]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1p15]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P15 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p15 OCA], [https://pdbe.org/1p15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p15 RCSB], [https://www.ebi.ac.uk/pdbsum/1p15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p15 ProSAT]</span></td></tr>
{{STRUCTURE_1p15|  PDB=1p15 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/PTPRA_MOUSE PTPRA_MOUSE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p1/1p15_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p15 ConSurf].
<div style="clear:both"></div>


===Crystal structure of the D2 domain of RPTPa===
==See Also==
 
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_12834342}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 12834342 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_12834342}}
 
==About this Structure==
1P15 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P15 OCA].
 
==Reference==
The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region., Sonnenburg ED, Bilwes A, Hunter T, Noel JP, Biochemistry. 2003 Jul 8;42(26):7904-14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12834342 12834342]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Bilwes A]]
[[Category: Single protein]]
[[Category: Hunter T]]
[[Category: Bilwes, A.]]
[[Category: Noel JP]]
[[Category: Hunter, T.]]
[[Category: Sonnenburg ED]]
[[Category: Noel, J P.]]
[[Category: Sonnenburg, E D.]]
[[Category: Hydrolase]]
[[Category: Phosphorylation]]
[[Category: Transmembrane]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:28:57 2008''
Retrieved from "https://proteopedia.org/1p15"