2gb7: Difference between revisions

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{{Seed}}
[[Image:2gb7.png|left|200px]]


<!--
==Metal-depleted Ecl18kI in complex with uncleaved, modified DNA==
The line below this paragraph, containing "STRUCTURE_2gb7", creates the "Structure Box" on the page.
<StructureSection load='2gb7' size='340' side='right'caption='[[2gb7]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2gb7]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GB7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GB7 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gb7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gb7 OCA], [https://pdbe.org/2gb7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gb7 RCSB], [https://www.ebi.ac.uk/pdbsum/2gb7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gb7 ProSAT]</span></td></tr>
{{STRUCTURE_2gb7|  PDB=2gb7 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/O87963_ENTCL O87963_ENTCL]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gb/2gb7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gb7 ConSurf].
<div style="clear:both"></div>


===Metal-depleted Ecl18kI in complex with uncleaved, modified DNA===
==See Also==
 
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_16628220}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 16628220 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_16628220}}
 
==About this Structure==
2GB7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GB7 OCA].
 
==Reference==
Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease., Bochtler M, Szczepanowski RH, Tamulaitis G, Grazulis S, Czapinska H, Manakova E, Siksnys V, EMBO J. 2006 May 17;25(10):2219-29. Epub 2006 Apr 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16628220 16628220]
 
Alternative arrangements of catalytic residues at the active sites of restriction enzymes., Tamulaitis G, Solonin AS, Siksnys V, FEBS Lett. 2002 May 8;518(1-3):17-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11997010 11997010]
 
The Ecl18kI restriction-modification system: cloning, expression, properties of the purified enzymes., Denjmukhametov MM, Brevnov MG, Zakharova MV, Repyk AV, Solonin AS, Petrauskene OV, Gromova ES, FEBS Lett. 1998 Aug 21;433(3):233-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9744801 9744801]
[[Category: Enterobacter cloacae]]
[[Category: Enterobacter cloacae]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Bochtler, M.]]
[[Category: Bochtler M]]
[[Category: Czapinska, H.]]
[[Category: Czapinska H]]
[[Category: Grazulis, S.]]
[[Category: Grazulis S]]
[[Category: Manakova, E.]]
[[Category: Manakova E]]
[[Category: Siksnys, V.]]
[[Category: Siksnys V]]
[[Category: Szczepanowski, R H.]]
[[Category: Szczepanowski RH]]
[[Category: Tamulaitis, G.]]
[[Category: Tamulaitis G]]
[[Category: Base extrusion]]
[[Category: Ecl18ki-dna complex]]
[[Category: Nucleotide flipping]]
[[Category: Type ii restriction endonuclease]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:33:34 2008''
Retrieved from "https://proteopedia.org/2gb7"