1sfc: Difference between revisions

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{{Seed}}
[[Image:1sfc.png|left|200px]]


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==NEURONAL SYNAPTIC FUSION COMPLEX==
The line below this paragraph, containing "STRUCTURE_1sfc", creates the "Structure Box" on the page.
<StructureSection load='1sfc' size='340' side='right'caption='[[1sfc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1sfc]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The November 2013 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''SNARE Proteins''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2013_11 10.2210/rcsb_pdb/mom_2013_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SFC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SFC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene></td></tr>
{{STRUCTURE_1sfc| PDB=1sfc |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sfc OCA], [https://pdbe.org/1sfc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sfc RCSB], [https://www.ebi.ac.uk/pdbsum/1sfc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sfc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VAMP2_RAT VAMP2_RAT] Involved in the targeting and/or fusion of transport vesicles to their target membrane (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sf/1sfc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sfc ConSurf].
<div style="clear:both"></div>


===NEURONAL SYNAPTIC FUSION COMPLEX===
==See Also==
 
*[[Syntaxin 3D structures|Syntaxin 3D structures]]
 
*[[Vesicle-associated membrane protein|Vesicle-associated membrane protein]]
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</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 9759724 is the PubMed ID number.
[[Category: Large Structures]]
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[[Category: RCSB PDB Molecule of the Month]]
{{ABSTRACT_PUBMED_9759724}}
 
==About this Structure==
1SFC is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SFC OCA].
 
==Reference==
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution., Sutton RB, Fasshauer D, Jahn R, Brunger AT, Nature. 1998 Sep 24;395(6700):347-53. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9759724 9759724]
[[Category: Protein complex]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Brunger, A T.]]
[[Category: SNARE Proteins]]
[[Category: Sutton, R B.]]
[[Category: Brunger AT]]
[[Category: Membrane fusion protein complex]]
[[Category: Sutton RB]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 15:36:35 2008''
Retrieved from "https://proteopedia.org/1sfc"