1eu0: Difference between revisions

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'''Theoretical Model'''
{{Theoretical_model}}


The entry 1EU0 is a Theoretical Model titled 'THEORETICAL MODEL OF THE HUMAN INVOLUCRIN (FRAGMENT, FROM 312 TO 361 POSITION)'.
==THEORETICAL MODEL OF THE HUMAN INVOLUCRIN (FRAGMENT, FROM 312 TO 361 POSITION)==
<StructureSection load='1eu0' size='340' side='right'caption='[[1eu0]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EU0 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eu0 FirstGlance], [https://www.ebi.ac.uk/pdbsum/1eu0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eu0 ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Involucrin is a key component of the cross-linked envelope of terminally differentiated keratinocytes. The human molecule largely consists of 10 residue repeats and forms a thin 460 A long rod. Summarized experimental data and a detailed stereochemical analysis made with computer modeling resulted in a structural model for the involucrin molecule. The suggested structure is a left-handed alpha-helical solenoid built of a tandem array of helix-turn-helix folds. The structure enables us to explain the whole set of experimental data and residue conservations within the repeats. It is ideally suited to serve as a scaffold for cell envelope assembly and proposes a possible mode of the intermolecular interactions of involucrin during cell cornification.


[[Category:Theoretical Model]]
alpha-Helical solenoid model for the human involucrin.,Kajava AV FEBS Lett. 2000 May 12;473(2):127-31. PMID:10812058<ref>PMID:10812058</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 30 09:49:36 2008''
</div>
<div class="pdbe-citations 1eu0" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Theoretical Model]]
[[Category: Large Structures]]
[[Category: Kajava, A V]]