1o0j: Difference between revisions
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{{Theoretical_model}} | |||
==HUMAN T-CELL LEUKEMIA VIRUS TYPE I PROTEASE (HTLV-I) WITH BOUND CAPSID/NUCLEOCAPSID (CA/NC) SUBSTRATE== | |||
<StructureSection load='1o0j' size='340' side='right'caption='[[1o0j]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O0J FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o0j FirstGlance], [https://www.ebi.ac.uk/pdbsum/1o0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o0j ProSAT]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Sequence alignment of human T-lymphotropic virus type I (HTLV-I) protease and other retroviral proteases reveals that the leukemia virus proteases contain residues at the C-terminus that are absent in the other proteases. We have prepared a mutant of HTLV-I protease that does not contain the 10 C-terminal residues and demonstrated that the catalytic efficiency of cleavage of a peptide substrate is unaffected. | |||
The 10 C-terminal residues of HTLV-I protease are not necessary for enzymatic activity.,Herger BE, Mariani VL, Dennison K, Shuker SB Biochem Biophys Res Commun. 2004 Aug 6;320(4):1306-8. PMID:15303275<ref>PMID:15303275</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 1o0j" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Theoretical Model]] | |||
[[Category: Large Structures]] | |||
[[Category: Dennison, K]] | |||
[[Category: Herger, B E]] | |||
[[Category: Shuker, S B]] | |||
Latest revision as of 07:07, 25 August 2021
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HUMAN T-CELL LEUKEMIA VIRUS TYPE I PROTEASE (HTLV-I) WITH BOUND CAPSID/NUCLEOCAPSID (CA/NC) SUBSTRATE
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