1t7g: Difference between revisions
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{{Theoretical_model}} | |||
The | ==THEORETICAL MODEL OF SARS CORONAVIRUS PEPLOMER== | ||
<StructureSection load='1t7g' size='340' side='right'caption='[[1t7g]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T7G FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t7g FirstGlance], [https://www.ebi.ac.uk/pdbsum/1t7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t7g ProSAT]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The tertiary structures of the S1 and S2 domains of the spike protein of the coronavirus which is responsible of the severe acute respiratory syndrome (SARS) have been recently predicted. Here a molecular assembly of SARS coronavirus peplomer which accounts for the available functional data is suggested. The interaction between S1 and S2 appears to be stabilised by a large hydrophobic network of aromatic side chains present in both domains. This feature results to be common to all coronaviruses, suggesting potential targeting for drugs preventing coronavirus-related infections. | |||
Prediction of quaternary assembly of SARS coronavirus peplomer.,Bernini A, Spiga O, Ciutti A, Chiellini S, Bracci L, Yan X, Zheng B, Huang J, He ML, Song HD, Hao P, Zhao G, Niccolai N Biochem Biophys Res Commun. 2004 Dec 24;325(4):1210-4. PMID:15555555<ref>PMID:15555555</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 1t7g" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Theoretical Model]] | |||
[[Category: Large Structures]] | |||
[[Category: Bernini, A]] | |||
[[Category: Bracci, L]] | |||
[[Category: Chiellini, S]] | |||
[[Category: Ciutti, A]] | |||
[[Category: Niccolai, N]] | |||
[[Category: Spiga, O]] | |||
Latest revision as of 09:23, 29 September 2021
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THEORETICAL MODEL OF SARS CORONAVIRUS PEPLOMER
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