3c71: Difference between revisions

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{{Seed}}
[[Image:3c71.jpg|left|200px]]


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==Structure of a ResA variant with a DsbA-like active site motif (CPHC)==
The line below this paragraph, containing "STRUCTURE_3c71", creates the "Structure Box" on the page.
<StructureSection load='3c71' size='340' side='right'caption='[[3c71]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3c71]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C71 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
{{STRUCTURE_3c71| PDB=3c71 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c71 OCA], [https://pdbe.org/3c71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c71 RCSB], [https://www.ebi.ac.uk/pdbsum/3c71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c71 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RESA_BACSU RESA_BACSU] Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. Does not play a role in sporulation.<ref>PMID:12637552</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/3c71_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c71 ConSurf].
<div style="clear:both"></div>


===Struture of a ResA variant with a DsbA-like active site motif (CPHC)===
==See Also==
 
*[[Protein disulfide oxidoreductase 3D structures|Protein disulfide oxidoreductase 3D structures]]
 
== References ==
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(as it appears on PubMed at http://www.pubmed.gov), where 18422485 is the PubMed ID number.
</StructureSection>
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{{ABSTRACT_PUBMED_18422485}}
 
==About this Structure==
3C71 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C71 OCA].
 
==Reference==
Effects of substitutions in the CXXC active-site motif of the extracytoplasmic thioredoxin ResA., Lewin A, Crow A, Hodson CT, Hederstedt L, Le Brun NE, Biochem J. 2008 Aug 15;414(1):81-91. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18422485 18422485]
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Crow, A.]]
[[Category: Crow A]]
[[Category: Cytochrome c-type biogenesis]]
[[Category: Membrane]]
[[Category: Oxidoreductase]]
[[Category: Redox-active center]]
[[Category: Signal-anchor]]
[[Category: Thioredoxin-like fold]]
[[Category: Transmembrane]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 13 13:59:31 2008''

Latest revision as of 09:33, 21 February 2024

Structure of a ResA variant with a DsbA-like active site motif (CPHC)

3c71, resolution 1.90Å

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