3ceq: Difference between revisions
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< | ==The TPR domain of Human Kinesin Light Chain 2 (hKLC2)== | ||
<StructureSection load='3ceq' size='340' side='right'caption='[[3ceq]], [[Resolution|resolution]] 2.75Å' scene=''> | |||
== Structural highlights == | |||
or the | <table><tr><td colspan='2'>[[3ceq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CEQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CEQ FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ceq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ceq OCA], [https://pdbe.org/3ceq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ceq RCSB], [https://www.ebi.ac.uk/pdbsum/3ceq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ceq ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KLC2_HUMAN KLC2_HUMAN] Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ce/3ceq_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ceq ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[Kinesin 3D Structures|Kinesin 3D Structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Bochkarev | [[Category: Bochkarev A]] | ||
[[Category: Bountra | [[Category: Bountra C]] | ||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: MacKenzie | [[Category: MacKenzie F]] | ||
[[Category: Park | [[Category: Park H]] | ||
[[Category: Shen Y]] | |||
[[Category: Shen | [[Category: Weigelt J]] | ||
[[Category: Weigelt | [[Category: Zhu H]] | ||
[[Category: Zhu | |||