1r7o: Difference between revisions

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New page: left|200px<br /><applet load="1r7o" size="450" color="white" frame="true" align="right" spinBox="true" caption="1r7o, resolution 1.85Å" /> '''Crystal Structure of...
 
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[[Image:1r7o.gif|left|200px]]<br /><applet load="1r7o" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1r7o, resolution 1.85&Aring;" />
'''Crystal Structure of apo-mannanase 26A from Psudomonas cellulosa'''<br />


==About this Structure==
==Crystal Structure of apo-mannanase 26A from Psudomonas cellulosa==
1R7O is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus] with ZN, SO4 and MES as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1R7O OCA].  
<StructureSection load='1r7o' size='340' side='right'caption='[[1r7o]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1r7o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R7O FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r7o OCA], [https://pdbe.org/1r7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r7o RCSB], [https://www.ebi.ac.uk/pdbsum/1r7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r7o ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MANA_CELJU MANA_CELJU] Hydrolyzes mannan and galactomannan, but displays little activity towards other polysaccharides located in the plant cell wall. Appears to act in synergy with alpha-galactosidase (AgaA) to elicit hydrolysis of galactomannan. Preferentially hydrolyzes the larger oligosaccharides and has greater activity against non-substituted polysaccharides.<ref>PMID:7848261</ref> <ref>PMID:11064195</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r7/1r7o_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r7o ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Mannosidase 3D structures|Mannosidase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Cellvibrio japonicus]]
[[Category: Cellvibrio japonicus]]
[[Category: Mannan endo-1,4-beta-mannosidase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Oakley AJ]]
[[Category: Oakley, A.J.]]
[[Category: Wilce MCJ]]
[[Category: Wilce, M.C.J.]]
[[Category: MES]]
[[Category: SO4]]
[[Category: ZN]]
[[Category: endo beta1-4 mannanase]]
[[Category: mannan degrading enzyme]]
[[Category: mannanase 26a]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 01:20:03 2007''
Retrieved from "https://proteopedia.org/1r7o"