3cky: Difference between revisions

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{{Seed}}
[[Image:3cky.png|left|200px]]


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==Structural and Kinetic Properties of a beta-hydroxyacid dehydrogenase involved in nicotinate fermentation==
The line below this paragraph, containing "STRUCTURE_3cky", creates the "Structure Box" on the page.
<StructureSection load='3cky' size='340' side='right'caption='[[3cky]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3cky]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Eubacterium_barkeri Eubacterium barkeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CKY FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cky OCA], [https://pdbe.org/3cky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cky RCSB], [https://www.ebi.ac.uk/pdbsum/3cky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cky ProSAT]</span></td></tr>
{{STRUCTURE_3cky|  PDB=3cky  |  SCENE=  }}
</table>
 
== Function ==
===Structural and Kinetic Properties of a beta-hydroxyacid dehydrogenase involved in nicotinate fermentation===
[https://www.uniprot.org/uniprot/HMGD_EUBBA HMGD_EUBBA] Catalyzes the conversion of 2-formylglutarate to (S)-2-hydroxymethylglutarate. Has very low activity with (S)-3-hydroxyisobutyrate.<ref>PMID:18680749</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_18680749}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 18680749 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ck/3cky_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_18680749}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cky ConSurf].
3CKY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Eubacterium_barkeri Eubacterium barkeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKY OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
Structural and Kinetic Properties of a beta-Hydroxyacid Dehydrogenase Involved in Nicotinate Fermentation., Reitz S, Alhapel A, Essen LO, Pierik AJ, J Mol Biol. 2008 Jul 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18680749 18680749]
__TOC__
[[Category: 2-hydroxymethylglutarate dehydrogenase]]
</StructureSection>
[[Category: Eubacterium barkeri]]
[[Category: Eubacterium barkeri]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Alhapel, A.]]
[[Category: Alhapel A]]
[[Category: Essen, L O.]]
[[Category: Essen L-O]]
[[Category: Pierik, A J.]]
[[Category: Pierik AJ]]
[[Category: Reitz, S.]]
[[Category: Reitz S]]
[[Category: Oxidoreductase]]
[[Category: Rossmann fold]]
[[Category: Two domain enzyme]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 10 09:02:30 2008''

Latest revision as of 09:36, 21 February 2024

Structural and Kinetic Properties of a beta-hydroxyacid dehydrogenase involved in nicotinate fermentation

3cky, resolution 2.30Å

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