3e9v: Difference between revisions

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New page: '''Unreleased structure''' The entry 3e9v is ON HOLD Authors: Sampathkumar, P., Romero, R., Wasserman, S., Hu, S., Maletic, M., Freeman, J., Tarun, G., Atwell, S., Sauder, J.M., Burley,...
 
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'''Unreleased structure'''


The entry 3e9v is ON HOLD
==Crystal structure of human B-cell Translocation Gene 2 (BTG2)==
 
<StructureSection load='3e9v' size='340' side='right'caption='[[3e9v]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
Authors: Sampathkumar, P., Romero, R., Wasserman, S., Hu, S., Maletic, M., Freeman, J., Tarun, G., Atwell, S., Sauder, J.M., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3e9v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E9V FirstGlance]. <br>
Description: Crystal structure of human B-cell Translocation Gene 2 (BTG2)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 10 12:34:54 2008''
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e9v OCA], [https://pdbe.org/3e9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e9v RCSB], [https://www.ebi.ac.uk/pdbsum/3e9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e9v ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3e9v TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BTG2_HUMAN BTG2_HUMAN] Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Anti-proliferative protein. Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth.<ref>PMID:12771185</ref> <ref>PMID:15788397</ref> <ref>PMID:18773938</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e9/3e9v_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e9v ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Atwell S]]
[[Category: Burley SK]]
[[Category: Freeman J]]
[[Category: Hu S]]
[[Category: Maletic M]]
[[Category: Romero R]]
[[Category: Sampathkumar P]]
[[Category: Sauder JM]]
[[Category: Tarun G]]
[[Category: Wasserman S]]
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