2z86: Difference between revisions

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{{Seed}}
[[Image:2z86.jpg|left|200px]]


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==Crystal structure of chondroitin polymerase from Escherichia coli strain K4 (K4CP) complexed with UDP-GlcUA and UDP==
The line below this paragraph, containing "STRUCTURE_2z86", creates the "Structure Box" on the page.
<StructureSection load='2z86' size='340' side='right'caption='[[2z86]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2z86]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z86 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z86 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene>, <scene name='pdbligand=UGA:URIDINE-5-DIPHOSPHATE-GLUCURONIC+ACID'>UGA</scene></td></tr>
{{STRUCTURE_2z86|  PDB=2z86  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z86 OCA], [https://pdbe.org/2z86 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z86 RCSB], [https://www.ebi.ac.uk/pdbsum/2z86 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z86 ProSAT]</span></td></tr>
 
</table>
===Crystal structure of chondroitin polymerase from Escherichia coli strain K4 (K4CP) complexed with UDP-GlcUA and UDP===
== Function ==
 
[https://www.uniprot.org/uniprot/CHS_ECOLX CHS_ECOLX] Glycosyltransferase that catalyzes elongation of chondroitin, a polysaccharide composed of a repeating disaccharide of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcUA) units, by alternatively transferring the GlcUA and GalNAc moiety from UDP-GlcUA and UDP-GalNAc to the non-reducing ends of the chondroitin chain. Each chondroitin unit has the composition beta-(1->4)-GlcUA-beta-(1->3)-GalNAc.<ref>PMID:11943778</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2Z86 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z86 OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z8/2z86_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z86 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Hirooka, R.]]
[[Category: Hirooka R]]
[[Category: Kakuta, Y.]]
[[Category: Kakuta Y]]
[[Category: Kimata, K.]]
[[Category: Kimata K]]
[[Category: Kimura, M.]]
[[Category: Kimura M]]
[[Category: Osawa, T.]]
[[Category: Osawa T]]
[[Category: Shimada, H.]]
[[Category: Shimada H]]
[[Category: Sugiura, N.]]
[[Category: Sugiura N]]
[[Category: Tsuji, A.]]
[[Category: Tsuji A]]
[[Category: Fold]]
[[Category: Glycosyltransferase some]]
[[Category: Gt-a]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 17 14:19:00 2008''
Retrieved from "https://proteopedia.org/2z86"