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{{Seed}}
[[Image:3ch4.png|left|200px]]


<!--
==The Crystal Structure of Human Phosphomavelonate Kinase At 1.8 A Resolution==
The line below this paragraph, containing "STRUCTURE_3ch4", creates the "Structure Box" on the page.
<StructureSection load='3ch4' size='340' side='right'caption='[[3ch4]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3ch4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CH4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CH4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3ch4|  PDB=3ch4  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ch4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ch4 OCA], [https://pdbe.org/3ch4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ch4 RCSB], [https://www.ebi.ac.uk/pdbsum/3ch4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ch4 ProSAT]</span></td></tr>
 
</table>
===The Crystal Structure of Human Phosphomavelonate Kinase At 1.8 A Resolution===
== Function ==
 
[https://www.uniprot.org/uniprot/PMVK_HUMAN PMVK_HUMAN]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
3CH4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CH4 OCA].  
Check<jmol>
 
  <jmolCheckbox>
==Reference==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ch/3ch4_consurf.spt"</scriptWhenChecked>
Crystal structure of human phosphomavelonate kinase at 1.8 A resolution., Chang Q, Yan XX, Gu SY, Liu JF, Liang DC, Proteins. 2008 Oct;73(1):254-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18618710 18618710]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ch4 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphomevalonate kinase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Chang Q]]
[[Category: Chang, Q.]]
[[Category: Gu S-Y]]
[[Category: Gu, S Y.]]
[[Category: Liang D-C]]
[[Category: Liang, D C.]]
[[Category: Yan X-X]]
[[Category: Yan, X X.]]
[[Category: Cholesterol biosynthesis]]
[[Category: Kinase]]
[[Category: Lipid synthesis]]
[[Category: Parallel beta-sheet with the strand order 23145]]
[[Category: Peroxisome]]
[[Category: Steroid biosynthesis]]
[[Category: Sterol biosynthesis]]
[[Category: Transferase]]
[[Category: Walker a motif]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Sep 18 10:03:32 2008''

Latest revision as of 14:04, 13 March 2024

The Crystal Structure of Human Phosphomavelonate Kinase At 1.8 A Resolution

3ch4, resolution 1.76Å

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