1sbq: Difference between revisions

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New page: left|200px<br /><applet load="1sbq" size="450" color="white" frame="true" align="right" spinBox="true" caption="1sbq, resolution 2.20Å" /> '''Crystal Structure of...
 
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[[Image:1sbq.gif|left|200px]]<br /><applet load="1sbq" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1sbq, resolution 2.20&Aring;" />
'''Crystal Structure of methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae at 2.2 resolution'''<br />


==About this Structure==
==Crystal Structure of methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae at 2.2 resolution==
1SBQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae] with SO4 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/5-formyltetrahydrofolate_cyclo-ligase 5-formyltetrahydrofolate cyclo-ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.3.2 6.3.3.2] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1SBQ OCA].  
<StructureSection load='1sbq' size='340' side='right'caption='[[1sbq]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
 
== Structural highlights ==
==Reference==
<table><tr><td colspan='2'>[[1sbq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SBQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SBQ FirstGlance]. <br>
Crystal structure of methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae (GI: 13508087) at 2.2 A resolution., Chen S, Shin DH, Pufan R, Kim R, Kim SH, Proteins. 2004 Sep 1;56(4):839-43. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15281135 15281135]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
[[Category: 5-formyltetrahydrofolate cyclo-ligase]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sbq OCA], [https://pdbe.org/1sbq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sbq RCSB], [https://www.ebi.ac.uk/pdbsum/1sbq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sbq ProSAT], [https://www.topsan.org/Proteins/BSGC/1sbq TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MTHFS_MYCPN MTHFS_MYCPN] Involved in folate metabolism. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate.<ref>PMID:16104022</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sb/1sbq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sbq ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycoplasma pneumoniae]]
[[Category: Mycoplasma pneumoniae]]
[[Category: Single protein]]
[[Category: Chen S]]
[[Category: BSGC, Berkeley.Structural.Genomics.Center.]]
[[Category: Kim R]]
[[Category: Chen, S.]]
[[Category: Kim SH]]
[[Category: Kim, R.]]
[[Category: Pufan R]]
[[Category: Kim, S.H.]]
[[Category: Shin DH]]
[[Category: Pufan, R.]]
[[Category: Shin, D.H.]]
[[Category: SO4]]
[[Category: 10-methenyltetrahydrofolate synthetase]]
[[Category: 5]]
[[Category: 5-formyltetrahydrofolate cyclo-ligase]]
[[Category: berkeley structural genomics center]]
[[Category: bsgc structure funded by nih]]
[[Category: mthfs]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomics]]
 
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