1sby: Difference between revisions

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New page: left|200px<br /><applet load="1sby" size="450" color="white" frame="true" align="right" spinBox="true" caption="1sby, resolution 1.10Å" /> '''Alcohol dehydrogenas...
 
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[[Image:1sby.gif|left|200px]]<br /><applet load="1sby" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1sby, resolution 1.10&Aring;" />
'''Alcohol dehydrogenase from Drosophila lebanonensis complexed with NAD+ and 2,2,2-trifluoroethanol at 1.1 A resolution'''<br />


==About this Structure==
==Alcohol dehydrogenase from Drosophila lebanonensis complexed with NAD+ and 2,2,2-trifluoroethanol at 1.1 A resolution==
1SBY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Scaptodrosophila_lebanonensis Scaptodrosophila lebanonensis] with NAD and ETF as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1SBY OCA].  
<StructureSection load='1sby' size='340' side='right'caption='[[1sby]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
[[Category: Alcohol dehydrogenase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[1sby]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Scaptodrosophila_lebanonensis Scaptodrosophila lebanonensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SBY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ETF:TRIFLUOROETHANOL'>ETF</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sby OCA], [https://pdbe.org/1sby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sby RCSB], [https://www.ebi.ac.uk/pdbsum/1sby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sby ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ADH_DROLE ADH_DROLE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sb/1sby_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sby ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Alcohol dehydrogenase 3D structures|Alcohol dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Scaptodrosophila lebanonensis]]
[[Category: Scaptodrosophila lebanonensis]]
[[Category: Single protein]]
[[Category: Atrian S]]
[[Category: Atrian, S.]]
[[Category: Benach J]]
[[Category: Benach, J.]]
[[Category: Gonzalez-Duarte R]]
[[Category: Gonzalez-Duarte, R.]]
[[Category: Ladenstein R]]
[[Category: Ladenstein, R.]]
[[Category: Lamzin VS]]
[[Category: Lamzin, V.S.]]
[[Category: Meijers R]]
[[Category: Meijers, R.]]
[[Category: ETF]]
[[Category: NAD]]
[[Category: alcohol dehydrogenase]]
[[Category: nad]]
[[Category: ternary complex]]
[[Category: trifluoroethanol]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 02:15:46 2007''
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