1x4b: Difference between revisions

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{{Seed}}
[[Image:1x4b.png|left|200px]]


<!--
==Solution structure of RRM domain in Heterogeneous nuclear ribonucleaoproteins A2/B1==
The line below this paragraph, containing "STRUCTURE_1x4b", creates the "Structure Box" on the page.
<StructureSection load='1x4b' size='340' side='right'caption='[[1x4b]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1x4b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X4B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X4B FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x4b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x4b OCA], [https://pdbe.org/1x4b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x4b RCSB], [https://www.ebi.ac.uk/pdbsum/1x4b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x4b ProSAT], [https://www.topsan.org/Proteins/RSGI/1x4b TOPSAN]</span></td></tr>
{{STRUCTURE_1x4b| PDB=1x4b |  SCENE= }}
</table>
== Disease ==
[https://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN] Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>
== Function ==
[https://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN] Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x4/1x4b_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x4b ConSurf].
<div style="clear:both"></div>


===Solution structure of RRM domain in Heterogeneous nuclear ribonucleaoproteins A2/B1===
==See Also==
 
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
 
== References ==
==About this Structure==
<references/>
1X4B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X4B OCA].
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: He, F.]]
[[Category: He F]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Muto, Y.]]
[[Category: Muto Y]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Shirouzu M]]
[[Category: Shirouzu, M.]]
[[Category: Terada T]]
[[Category: Terada, T.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: Heterogeneous nuclear ribonucleoproteins a2/b1]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nmr]]
[[Category: Nppsfa]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rrm domain]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Structure genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 29 04:42:08 2008''
Retrieved from "https://proteopedia.org/1x4b"