2htt: Difference between revisions

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{{Seed}}
[[Image:2htt.png|left|200px]]


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==Ruthenium Hexammine ion interactions with Z-DNA==
The line below this paragraph, containing "STRUCTURE_2htt", creates the "Structure Box" on the page.
<StructureSection load='2htt' size='340' side='right'caption='[[2htt]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2htt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HTT FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NRU:RUTHENIUM+(III)+HEXAAMINE+ION'>NRU</scene></td></tr>
{{STRUCTURE_2htt|  PDB=2htt  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2htt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2htt OCA], [https://pdbe.org/2htt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2htt RCSB], [https://www.ebi.ac.uk/pdbsum/2htt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2htt ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The hexamer duplex d(CGCGCA).d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 A resolution. Strong ion interactions with the adenine base induce a tautomeric shift from the amino to the imino form. Consequently, the A.T base pairing is disrupted. This structural study may be relevant to metal toxicity.


===Ruthenium Hexammine ion interactions with Z-DNA===
Hexammineruthenium(III) ion interactions with Z-DNA.,Bharanidharan D, Thiyagarajan S, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt, 12):1008-13. Epub 2007 Nov 21. PMID:18084080<ref>PMID:18084080</ref>


From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2htt" style="background-color:#fffaf0;"></div>


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==See Also==
The line below this paragraph, {{ABSTRACT_PUBMED_18084080}}, adds the Publication Abstract to the page
*[[Z-DNA|Z-DNA]]
(as it appears on PubMed at http://www.pubmed.gov), where 18084080 is the PubMed ID number.
== References ==
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<references/>
{{ABSTRACT_PUBMED_18084080}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
2HTT is a [[Protein complex]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTT OCA].
[[Category: Bharanidharan D]]
 
[[Category: Gautham N]]
==Reference==
[[Category: Thiyagarajan S]]
Hexammineruthenium(III) ion interactions with Z-DNA., Bharanidharan D, Thiyagarajan S, Gautham N, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt, 12):1008-13. Epub 2007 Nov 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18084080 18084080]
[[Category: Protein complex]]
[[Category: Bharanidharan, D.]]
[[Category: Gautham, N.]]
[[Category: Thiyagarajan, S.]]
[[Category: Double helix]]
[[Category: Z-dna]]
 
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