3e9v: Difference between revisions

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{{Seed}}
[[Image:3e9v.jpg|left|200px]]


<!--
==Crystal structure of human B-cell Translocation Gene 2 (BTG2)==
The line below this paragraph, containing "STRUCTURE_3e9v", creates the "Structure Box" on the page.
<StructureSection load='3e9v' size='340' side='right'caption='[[3e9v]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3e9v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E9V FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
{{STRUCTURE_3e9v|  PDB=3e9v  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e9v OCA], [https://pdbe.org/3e9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e9v RCSB], [https://www.ebi.ac.uk/pdbsum/3e9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e9v ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3e9v TOPSAN]</span></td></tr>
 
</table>
===Crystal structure of human B-cell Translocation Gene 2 (BTG2)===
== Function ==
 
[https://www.uniprot.org/uniprot/BTG2_HUMAN BTG2_HUMAN] Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Anti-proliferative protein. Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth.<ref>PMID:12771185</ref> <ref>PMID:15788397</ref> <ref>PMID:18773938</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
3E9V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E9V OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e9/3e9v_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e9v ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Atwell, S.]]
[[Category: Atwell S]]
[[Category: Burley, S K.]]
[[Category: Burley SK]]
[[Category: Freeman, J.]]
[[Category: Freeman J]]
[[Category: Hu, S.]]
[[Category: Hu S]]
[[Category: Maletic, M.]]
[[Category: Maletic M]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
[[Category: Romero R]]
[[Category: Romero, R.]]
[[Category: Sampathkumar P]]
[[Category: Sampathkumar, P.]]
[[Category: Sauder JM]]
[[Category: Sauder, J M.]]
[[Category: Tarun G]]
[[Category: Tarun, G.]]
[[Category: Wasserman S]]
[[Category: Wasserman, S.]]
[[Category: Antiproliferative protein]]
[[Category: B-cell translocation gene 2]]
[[Category: Btg2]]
[[Category: New york sgx research center for structural genomic]]
[[Category: New york structural genomix research consortium]]
[[Category: Nysgxrc]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulator]]
[[Category: Tumour supressor]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 15 15:35:31 2008''

Latest revision as of 12:59, 30 August 2023

Crystal structure of human B-cell Translocation Gene 2 (BTG2)

3e9v, resolution 1.70Å

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