1te2: Difference between revisions
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New page: left|200px<br /><applet load="1te2" size="450" color="white" frame="true" align="right" spinBox="true" caption="1te2, resolution 1.76Å" /> '''Putative Phosphatase... |
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== | ==Putative Phosphatase Ynic from Escherichia coli K12== | ||
<StructureSection load='1te2' size='340' side='right'caption='[[1te2]], [[Resolution|resolution]] 1.76Å' scene=''> | |||
[[ | == Structural highlights == | ||
[ | <table><tr><td colspan='2'>[[1te2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TE2 FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76Å</td></tr> | |||
[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PGA:2-PHOSPHOGLYCOLIC+ACID'>PGA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1te2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1te2 OCA], [https://pdbe.org/1te2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1te2 RCSB], [https://www.ebi.ac.uk/pdbsum/1te2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1te2 ProSAT], [https://www.topsan.org/Proteins/MCSG/1te2 TOPSAN]</span></td></tr> | |||
</table> | |||
[[ | == Function == | ||
[ | [https://www.uniprot.org/uniprot/HXPB_ECOLI HXPB_ECOLI] Sugar-phosphate phosphohydrolase that catalyzes the dephosphorylation of D-mannitol 1-phosphate and D-sorbitol 6-phosphate (PubMed:27941785). Also catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate (2dGlu6P); this is a biologically important activity in vivo since it contributes to the elimination of this toxic compound and plays an important role in the resistance of E.coli to 2-deoxyglucose (PubMed:16990279). To a lesser extent, is also able to dephosphorylate mannose 6-phosphate (Man6P), erythrose-4-phosphate, 2-deoxyribose-5-phosphate (2dRib5P), ribose-5-phosphate (Rib5P) and glucose-6-phosphate (Glu6P) in vitro (PubMed:16990279).<ref>PMID:15808744</ref> <ref>PMID:16990279</ref> <ref>PMID:27941785</ref> | ||
[ | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
[[Category: | <jmolCheckbox> | ||
[[Category: | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/te/1te2_consurf.spt"</scriptWhenChecked> | ||
[[Category: | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
[[Category: | <text>to colour the structure by Evolutionary Conservation</text> | ||
[[Category: | </jmolCheckbox> | ||
[[Category: | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1te2 ConSurf]. | ||
[[Category: | <div style="clear:both"></div> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Edwards A]] | |||
[[Category: Evdokimova E]] | |||
[[Category: Joachimiak A]] | |||
[[Category: Kim Y]] | |||
[[Category: Savchenko A]] | |||
Latest revision as of 04:54, 17 October 2024
Putative Phosphatase Ynic from Escherichia coli K12
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