1th2: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
New page: left|200px<br /><applet load="1th2" size="450" color="white" frame="true" align="right" spinBox="true" caption="1th2, resolution 2.80Å" /> '''crystal structure of...
 
OCA (talk | contribs)
No edit summary
 
(16 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1th2.gif|left|200px]]<br /><applet load="1th2" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1th2, resolution 2.80&Aring;" />
'''crystal structure of NADPH depleted bovine liver catalase complexed with azide'''<br />


==About this Structure==
==crystal structure of NADPH depleted bovine liver catalase complexed with azide==
1TH2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with AZI and HEM as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1TH2 OCA].  
<StructureSection load='1th2' size='340' side='right'caption='[[1th2]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1th2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TH2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TH2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1th2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1th2 OCA], [https://pdbe.org/1th2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1th2 RCSB], [https://www.ebi.ac.uk/pdbsum/1th2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1th2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CATA_BOVIN CATA_BOVIN] Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/th/1th2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1th2 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Catalase 3D structures|Catalase 3D structures]]
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Catalase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Balasundaresan D]]
[[Category: Balasundaresan, D.]]
[[Category: Kumaran D]]
[[Category: Kumaran, D.]]
[[Category: Ponnuswamy MN]]
[[Category: Ponnuswamy, M.N.]]
[[Category: Sekar K]]
[[Category: Sekar, K.]]
[[Category: Sugadev R]]
[[Category: Sugadev, R.]]
[[Category: Swaminathan S]]
[[Category: Swaminathan, S.]]
[[Category: AZI]]
[[Category: HEM]]
[[Category: azide]]
[[Category: bovine liver catalase]]
[[Category: nadph]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 03:15:26 2007''

Latest revision as of 09:42, 25 December 2024

crystal structure of NADPH depleted bovine liver catalase complexed with azide

1th2, resolution 2.80Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA