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New page: left|200px<br /><applet load="1tkj" size="450" color="white" frame="true" align="right" spinBox="true" caption="1tkj, resolution 1.15Å" /> '''Streptomyces griseus...
 
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[[Image:1tkj.gif|left|200px]]<br /><applet load="1tkj" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1tkj, resolution 1.15&Aring;" />
'''Streptomyces griseus aminopeptidase complexed with D-Methionine'''<br />


==About this Structure==
==Streptomyces griseus aminopeptidase complexed with D-Methionine==
1TKJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_chryseus Streptomyces chryseus] with ZN, CA and MED as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1TKJ OCA].  
<StructureSection load='1tkj' size='340' side='right'caption='[[1tkj]], [[Resolution|resolution]] 1.15&Aring;' scene=''>
[[Category: Single protein]]
== Structural highlights ==
[[Category: Streptomyces chryseus]]
<table><tr><td colspan='2'>[[1tkj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TKJ FirstGlance]. <br>
[[Category: Blumberg, S.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15&#8491;</td></tr>
[[Category: Gilboa, R.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MED:D-METHIONINE'>MED</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Reiland, V.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tkj OCA], [https://pdbe.org/1tkj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tkj RCSB], [https://www.ebi.ac.uk/pdbsum/1tkj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tkj ProSAT]</span></td></tr>
[[Category: Schomburg, D.]]
</table>
[[Category: Shoham, G.]]
== Function ==
[[Category: Shoham, Y.]]
[https://www.uniprot.org/uniprot/APX_STRGG APX_STRGG] An exopeptidase specific for larger hydrophobic amino acids (especially leucine), no cleavage occurs if the next residue is proline (PubMed:8444149).<ref>PMID:2503378</ref> <ref>PMID:8444149</ref> <ref>PMID:8665903</ref>
[[Category: Spungin-Bialik, A.]]
== Evolutionary Conservation ==
[[Category: CA]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: MED]]
Check<jmol>
[[Category: ZN]]
  <jmolCheckbox>
[[Category: calcium activation]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tk/1tkj_consurf.spt"</scriptWhenChecked>
[[Category: double-zinc metalloproteinase]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: protein-inhibitor complex]]
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tkj ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 03:21:24 2007''
==See Also==
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
*[[Streptomyces griseus Aminopeptidase (SGAP)|Streptomyces griseus Aminopeptidase (SGAP)]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptomyces griseus]]
[[Category: Blumberg S]]
[[Category: Gilboa R]]
[[Category: Reiland V]]
[[Category: Schomburg D]]
[[Category: Shoham G]]
[[Category: Shoham Y]]
[[Category: Spungin-Bialik A]]
Retrieved from "https://proteopedia.org/1tkj"