2ivq: Difference between revisions

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{{Seed}}
[[Image:2ivq.jpg|left|200px]]


<!--
==SITE DIRECTED MUTAGENESIS OF KEY RESIDUES INVOLVED IN THE CATALYTIC MECHANISM OF CYANASE==
The line below this paragraph, containing "STRUCTURE_2ivq", creates the "Structure Box" on the page.
<StructureSection load='2ivq' size='340' side='right'caption='[[2ivq]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ivq]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IVQ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_2ivq|  PDB=2ivq  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ivq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ivq OCA], [https://pdbe.org/2ivq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ivq RCSB], [https://www.ebi.ac.uk/pdbsum/2ivq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ivq ProSAT]</span></td></tr>
 
</table>
===SITE DIRECTED MUTAGENESIS OF KEY RESIDUES INVOLVED IN THE CATALYTIC MECHANISM OF CYANASE===
== Function ==
 
[https://www.uniprot.org/uniprot/CYNS_ECOLI CYNS_ECOLI] Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_10801492}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 10801492 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iv/2ivq_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_10801492}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2IVQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVQ OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ivq ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Structure of cyanase reveals that a novel dimeric and decameric arrangement of subunits is required for formation of the enzyme active site., Walsh MA, Otwinowski Z, Perrakis A, Anderson PM, Joachimiak A, Structure. 2000 May 15;8(5):505-14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10801492 10801492]
</StructureSection>
[[Category: Cyanase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Anderson, P M.]]
[[Category: Anderson PM]]
[[Category: Guilloton, M.]]
[[Category: Guilloton M]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak A]]
[[Category: Walsh, M A.]]
[[Category: Walsh MA]]
[[Category: Cyanate degradation]]
[[Category: Lyase]]
[[Category: Mcsg]]
[[Category: Midwest center for structural genomic]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 29 10:42:02 2008''
Retrieved from "https://proteopedia.org/2ivq"