2k36: Difference between revisions

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{{Seed}}
[[Image:2k36.jpg|left|200px]]


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==Structure ensemble Backbone and side-chain 1H, 13C, and 15N Chemical Shift Assignments, 1H-15N RDCs and 1H-1H nOe restraints for protein K7 from the Vaccinia virus==
The line below this paragraph, containing "STRUCTURE_2k36", creates the "Structure Box" on the page.
<StructureSection load='2k36' size='340' side='right'caption='[[2k36]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2k36]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K36 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k36 OCA], [https://pdbe.org/2k36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k36 RCSB], [https://www.ebi.ac.uk/pdbsum/2k36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k36 ProSAT]</span></td></tr>
{{STRUCTURE_2k36|  PDB=2k36  |  SCENE=  }}
</table>
 
== Function ==
===Structure ensemble Backbone and side-chain 1H, 13C, and 15N Chemical Shift Assignments, 1H-15N RDCs and 1H-1H nOe restraints for protein K7 from the Vaccinia virus===
[https://www.uniprot.org/uniprot/K7_VACCW K7_VACCW] Bcl-2-like protein which, through its interaction with the DEAD box RNA helicase DDX3X/DDX3, prevents TBK1/IKKepsilon-mediated IRF3 activation. Contributes to virulence by binding to the host TRAF6 and IRAK2 and preventing host NF-kappa-B activation.
 
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_18845156}}
 
==About this Structure==
2K36 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K36 OCA].  
 
==Reference==
Poxvirus K7 Protein Adopts a Bcl-2 Fold: Biochemical Mapping of Its Interactions with Human DEAD Box RNA Helicase DDX3., Kalverda AP, Thompson GS, Vogel A, Schroder M, Bowie AG, Khan AR, Homans SW, J Mol Biol. 2008 Sep 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18845156 18845156]
[[Category: Single protein]]
[[Category: Vaccinia virus]]
[[Category: Vaccinia virus]]
[[Category: Bowie, A G.]]
[[Category: Bowie AG]]
[[Category: Homans, S W.]]
[[Category: Homans SW]]
[[Category: Kalverda, A P.]]
[[Category: Kalverda AP]]
[[Category: Khan, A R.]]
[[Category: Khan AR]]
[[Category: Thompson, G S.]]
[[Category: Schr der M]]
[[Category: Vogel, A.]]
[[Category: Thompson GS]]
[[Category: Der, M Schr.]]
[[Category: Vogel A]]
[[Category: Protein]]
[[Category: Viral protein]]
 
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